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Argyria
By; Eric Nietzel
What is Argyria?    Caused by a chemical
                       exposure to silver
                       (through ingestion or
                       exposure)
                      Binds with the cells usually
                       binding to selenium molecules
                      Symptoms exacerbate when
                       sunlight oxidizes the silver
                      May stimulate pigment
                       production
                      Much like an “all over tattoo”
                      Can develop small amounts
                       from procedures such as
                       accupuncture.
Signs and
Symptoms
•   Staining of the gums and
    mucosal layers
•   Gray-black staining of the skin
    (can be extensive or minute)
•   Some believe there is tissue
    damage but there is not
    enough research to confirm
    this
Diagnostic tests
•Fluorescent X-ray
•Skin Tissue Biopsy
•Medical History
Is there a Genetic
Disposition?
•No genetic disposition however
there are other factors that may
contribute to this process.
•Low Vitamin E and Selenium.
•People with slower metabolisms
•The use of certain remedies
passed down from family
member.
Expected
     Outcomes?
•Most of the time it is
irreversible depending on
the severity of symptoms
•Use of Hydroquinone (
a skin lotion )
•Use of Lasers to remove
pigmented skin/cells
Nursing
      Implications

•Thorough Medical history
•Proper nutrition
•Instruct patient about the use of
sunscreen
•Educate patient about the side
effects related to the use of
certain CAM
•Teach patient coping skills to deal
with body image changes
•Refer patients to Support Groups
•Educate patient about the
disease and its course
References
Unknown. (2007, December 22). Argyria cured [Online forum comment]. Retrieved from
          http://www.indiadivine.org/audarya/ayurveda-health-wellbeing/1042014-argyria-cured-
          curing-

Padelwaski, K. (2011, August 12). Argyia. Retrieved from /emedicine.medscape.com/article/1069121-
           overview

Chang, H. S., Han, T. Y., Lee, H. K., & Son, S.-J. (2011). Successful treatment ofargyriausing a low-
           fluenceQ-switched 1064-nm Nd:YAG laser.International Journal of Dermatology, 50(6), 751+.

Silver nitrate: argyria in an elderly patient: case report. (2009, May 16). Reactions   Weekly, (1252), 38.

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Everything You Need to Know About Argyria

  • 2. What is Argyria?  Caused by a chemical exposure to silver (through ingestion or exposure)  Binds with the cells usually binding to selenium molecules  Symptoms exacerbate when sunlight oxidizes the silver  May stimulate pigment production  Much like an “all over tattoo”  Can develop small amounts from procedures such as accupuncture.
  • 3. Signs and Symptoms • Staining of the gums and mucosal layers • Gray-black staining of the skin (can be extensive or minute) • Some believe there is tissue damage but there is not enough research to confirm this
  • 4. Diagnostic tests •Fluorescent X-ray •Skin Tissue Biopsy •Medical History
  • 5. Is there a Genetic Disposition? •No genetic disposition however there are other factors that may contribute to this process. •Low Vitamin E and Selenium. •People with slower metabolisms •The use of certain remedies passed down from family member.
  • 6. Expected Outcomes? •Most of the time it is irreversible depending on the severity of symptoms •Use of Hydroquinone ( a skin lotion ) •Use of Lasers to remove pigmented skin/cells
  • 7. Nursing Implications •Thorough Medical history •Proper nutrition •Instruct patient about the use of sunscreen •Educate patient about the side effects related to the use of certain CAM •Teach patient coping skills to deal with body image changes •Refer patients to Support Groups •Educate patient about the disease and its course
  • 8. References Unknown. (2007, December 22). Argyria cured [Online forum comment]. Retrieved from http://www.indiadivine.org/audarya/ayurveda-health-wellbeing/1042014-argyria-cured- curing- Padelwaski, K. (2011, August 12). Argyia. Retrieved from /emedicine.medscape.com/article/1069121- overview Chang, H. S., Han, T. Y., Lee, H. K., & Son, S.-J. (2011). Successful treatment ofargyriausing a low- fluenceQ-switched 1064-nm Nd:YAG laser.International Journal of Dermatology, 50(6), 751+. Silver nitrate: argyria in an elderly patient: case report. (2009, May 16). Reactions Weekly, (1252), 38.