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Pharmacokinetics:
Bioavailability
good
Metabolism
via pulmonary capillary bed
Biological half-life
2–6 seconds
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We estimate that the extravascular half-life of NO will range from 0.09 to > 2 s, depending on O2 concentration and thus distance from the vessel. Computer ...
The half-life of NO in blood has been estimated in the range of 0.05–1.8 ms [11], [58].
We estimate that the extravascular half-life of NO will range from 0.09 to > 2 s, depending on O 2 concentration and thus distance from the vessel.
Under our experimental conditions (PO2 = 40 mmHg), NO concentration fell slowly over 20 min with a half-life of 445 s. However, when haemoglobin was added, NO ...
The half life of nitric oxide is considered to be very small (3–6 s). Nitric oxide is involved in different physiological processes of the body by modulating ...
Half-life. 2–6 seconds. Clearance. Not Available. Adverse Effects. Improve ... The risk or severity of methemoglobinemia can be increased when Nitric Oxide is ...
Under our experimental conditions , NO concentration fell slowly over 20 min with a half-life of 445 s. However, when haemoglobin was added, NO disappeared ...
Oct 26, 1978 ˇ At concentrations of 100 p.p.m. or greater (as in some studies) the half life for oxidation of NO to NO2 by atmospheric oxygen is one hour or ...
Abstract. Nitric oxide (NO) has been linked to many regulatory functions in mammalian cells. Studies of NO release are hampered by the short half-life of ...